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Consists of individual items acquired separately either as a gift, purchase, transfer, or removal from a variety of sources, relating to English literature. Additions continue to be made.

The Sieveking mss., 1724-1971, consists of the papers of Lancelot (Lance) de Giberne Sieveking, 1896-1974, author, playwright, and pioneer of BBC radio programming.

The Stevens mss., 1749-1916, consist of papers of William Arnold Stevens, 1839-1910, his wife, Mrs. Caroline (Clarke) Stevens, 1834-1916, and members of their respective families.

The McCulloch mss., 1766-1914, consist of letters and papers of Hugh McCulloch, 1808-1895, U.S. Comptroller of the Currency, Secretary of the Treasury, and a partner in the London banking house of Jay Cooke, McCulloch & Company.

The Gwatkin mss., 1773-1780, consists of letters from educators Sarah More, 1743-1817, and Martha More, 1750-1819, to their patron, heiress Ann Lovell Gwatkin, 1729-1809.

The Holland mss., 1781-1953, consists of correspondence and papers of three generations of Holland family physicians from Bloomington, Indiana: Philip Calphy Holland, 1840-1929, his son, George Frank Holland, 1871-1936, and his son, Philip Todd Holland, 1905-1973.

The American literature mss., 1789-2000, consists of an ongoing collection of individual items related to American literature.

The Ellison mss., 1790-1949, consist of materials compiled by Robert Spurrier Ellison.

The Boone mss., 1791-1868, consists of the letters and papers of lawyer, teacher, merchant, and politician Benjamin Pennebaker Douglass, 1820-1904, and his second wife, Queen Victoria Boone, 1837-1885.

The Stevens mss. II, 1805-1911, consist of the correspondence of teacher and editor John Stevens, 1798-1877, and of members of his family.

The Barnhart mss., 1813-1962, consists of the papers of history scholar John Donald Barnhart, 1895-1967.

The Davis mss., 1814-1902, consists of the letters and papers of Emily Davis, teacher and Quaker, of Liberty, Indiana.

The Smith, H.W. mss., 1817-1987, consists of the letters of reformer Hannah Whitall Smith, 1832-1911, her daughters, art historian Mary Berenson, 1864-1945, and relief organizer Alys Whitall Pearsall Russell, 1867-1951, and her granddaughters, suffragist Ray Strachey, 1887-1940, and psychologist Karin Stephen, 1889–1953.

The Smith-Marsters mss., 1828-1905, are letters and papers of Hezekiah Smith, 1805-1879, Indiana Methodist circuit rider; his wife, Susan Davis (Marsters) Smith, 1819-1907; his wife's father, Stephen Marsters, 1795-1874, Methodist church elder; and members of their families.

The Griffith mss., 1831-1881, consists of the papers of physician Thomas Jefferson Griffith, 1837-1924, and his wife, physician Martha Hutchings Griffith, 1842-1923.

The Lane, J. mss., 1835-1906, consist of correspondence and papers of Joseph Lane, 1801-1881, first territorial governor of Oregon.

The Champ mss., 1836-1931, consists of the papers of Indiana physician, businessman, and postmaster George W. Champ, 1830-1905.

The Wharton mss., 1836-1975 (bulk 1900-1937), consists of the correspondence, diaries, and writings of novelist Edith Newbold Jones Wharton, 1862-1937.

The Bartholomew mss., 1838-1886, consists of the papers of American businessman, pioneer, and judicial officer Jacob Bartholomew, 1818-1863, and his wife, Emily Ebersole Bartholomew, 1825-1913.

The Tuttle mss., 1838-1912, are papers of Elizabeth A. Tuttle, 1823?-1896, nurse and teacher of Colebrook, Ohio, and of Ira Norris Noland, 1844?- , physician, who married Hattie Tuttle, niece of Elizabeth A. Tuttle.