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The Cookery mss., circa 1660–circa 1918, consists of bound and individual writings, often on the topic of cookery, of persons involved with cooking by practice or trade.

The McCulloch mss., 1766-1914, consist of letters and papers of Hugh McCulloch, 1808-1895, U.S. Comptroller of the Currency, Secretary of the Treasury, and a partner in the London banking house of Jay Cooke, McCulloch & Company.

The Boone mss., 1791-1868, consists of the letters and papers of lawyer, teacher, merchant, and politician Benjamin Pennebaker Douglass, 1820-1904, and his second wife, Queen Victoria Boone, 1837-1885.

Consists of individual items acquired separately either as a gift, purchase, transfer, or removal from a variety of sources, relating to English literature. Additions continue to be made.

The American literature mss., 1789-2000, consists of an ongoing collection of individual items related to American literature.

The Ellison mss., 1790-1949, consist of materials compiled by Robert Spurrier Ellison.

The Holland mss., 1781-1953, consists of correspondence and papers of three generations of Holland family physicians from Bloomington, Indiana: Philip Calphy Holland, 1840-1929, his son, George Frank Holland, 1871-1936, and his son, Philip Todd Holland, 1905-1973.

The Gwatkin mss., 1773-1780, consists of letters from educators Sarah More, 1743-1817, and Martha More, 1750-1819, to their patron, heiress Ann Lovell Gwatkin, 1729-1809.

The Sieveking mss., 1724-1971, consists of the papers of Lancelot (Lance) de Giberne Sieveking, 1896-1974, author, playwright, and pioneer of BBC radio programming.

The Stevens mss., 1749-1916, consist of papers of William Arnold Stevens, 1839-1910, his wife, Mrs. Caroline (Clarke) Stevens, 1834-1916, and members of their respective families.