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The Cleland mss., 1911-1946, consists of the papers of botanist Ralph Erskine Cleland, 1892-1971. They consist chiefly of correspondence with prominent scientists on Oenothera, evening primrose.

The Holland mss., 1781-1953, consists of correspondence and papers of three generations of Holland family physicians from Bloomington, Indiana: Philip Calphy Holland, 1840-1929, his son, George Frank Holland, 1871-1936, and his son, Philip Todd Holland, 1905-1973.

The Langer mss., 1940-1976, consist of the professional papers and reprints of Lawrence Marvin Langer, 1913-2000, physicist and Professor Emeritus of Physics at Indiana University.

The Miscellaneous mss., 2100 BCE-1970, consist of individual items acquired individually either as a gift or purchased from a variety of sources.

The Waddell mss., 1944-1987, consists of the World War II correspondence between geologist (Byron) Courtney Waddell, 1916-2003, and his fiancée and then wife, Australian-born Lola Yvonne Line, 1918-1998.