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This project is a compilation of interviews of subjects with strong ties to and memories of Indiana University, primarily at the Bloomington campus. The interviewees include former students, faculty, and staff, among others. The information contained in the interviews generally spans a little more than the first half of the twentieth century and often deals with the administrations under presidents William Lowe Bryan and Herman B Wells. The project is a survey of Indiana University's history as a whole including information about various academic departments, athletics, student organizations, campus growth, university development, living conditions, segregation and the treatment of African-Americans, the administration, and the importance of jazz at Indiana University. In addition, the impact of specific events, such as the Great Depression, World War I, World War II, the Vietnam War, and water shortages, is detailed in many of the interviews in this project.

The Indiana University School of Medicine emerged from a number of private, proprietary medical schools that existed in Indianapolis in the nineteenth and early-twentieth centuries. The most important of these private medical schools were the Medical College of Indiana and the College of Physicians and Surgeons, both of which operated in Indianapolis. In the first decade of the twentieth century efforts began to try to merge these private schools under the state universities then in Indiana, Purdue University and Indiana University. The merger of several medical schools under Purdue University was short-lived. In 1903 Indiana University established first year (classroom) medical studies at Bloomington, and in 1907 merged with the Medical College of Indiana and the remnant of the Purdue medical school to establish clinical instruction in Indianapolis. In subsequent years the School of Medicine was housed in Indianapolis on a large campus with several hospitals, clinical, and research facilities. First year medical studies were moved to Indianapolis by the 1950s.