The Blair, M.A.I. mss., 1684-1897, consists of letters and documents collected by art collector and benefactor Mary Anne Italia Mitchell Blair, 1855-1940.
The Signers of the Declaration of Independence mss., 1848, consists of materials pertaining to the members of the Continental Congress who drafted and signed the Declaration of Independence.
The Lafayette mss. IV, 1825-1860, consist of two letters. One is written by the Marquis de Lafayette, Marie Joseph Paul Yves Roch Gilbert du Motier, 1757-1834, general, to Elisha Ely. The second is written by John F. Ely to John Stoner Ely regarding the Marquis de Lafayette's travel plans.
The Meigs mss., 1794–1831, cpnsists of letters and papers of Return Jonathan Meigs, 1764–1825, governor of Ohio, United States senator, and postmaster general during the administrations of Presidents James Madison and James Monroe.
The Lafayette mss. II, 1774-1957, are individual letters and documents relating to the Marquis de Lafayette, Marie Joseph Paul Yves Roch Gilbert du Motier, 1757-1834, general, which have been acquired from several sources.
The U.S. History mss., 1612-1977, consist of individual items acquired separately either as a gift, purchase, transfer, or removal from a variety of sources, relating to the United States. Additions continue to be made.
The Sharpe mss., 1733-1755, consists of papers from the office of John Sharpe, 1700-1756, London solicitor for the British West Indies, relating to the enforcement of the 1733 Molasses Act.
The Indiana History mss., 1725-1973, consists of individual items related to the history of the state of Indiana, acquired separately either as a gift, purchase, transfer, or removal from a variety of sources.
The Cooper, M. mss., 1965-1992, consists primarily of letters and holiday cards from colonial historian, Charles Ralph Boxer, 1904-2000, to Jesuit author and editor Michael Cooper discussing writing projects of both men, mutual friends, activities and travels.