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The Lilly Correspondence mss., 1919-1954, consists of the correspondence of Josiah Kirby Lilly, Jr., 1893-1966, corporation executive of the Lilly Pharmaceutical Company of Indianapolis, Indiana, with bookdealers and individuals concerning the purchase of books, manuscripts, portraits, and prints. This correspondence reveals J.K. Lilly's many interests, among these Edgar Allan Poe and James Whitcomb Riley, the construction and equipment of Eaglecrest Libray at his home, and his membership in the Grolier Club.

The Ralston, S.M. mss., 1868-1928, consists of the papers of Indiana Governor and U.S. Senator, Samuel Moffett Ralston, 1857-1925.

The U.S. History mss., 1612-1977, consist of individual items acquired separately either as a gift, purchase, transfer, or removal from a variety of sources, relating to the United States. Additions continue to be made.