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Indiana University started offering regular classes in Indianapolis in 1891. An Extension Division was created in 1912 and began to offer a small number of courses for credit. A gradual increase of class offerings and enrollments in Indianapolis occurred in the following decades. The university occupied a variety of buildings in downtown Indianapolis over the years in what over time became known as the Downtown Campus (DTC). Courses in liberal arts, social sciences, mathematics, and the natural sciences were offered by the Downtown Campus, whereas Indiana University's professional schools located in Indianapolis (i.e., the Schools of Medicine, Dentistry, and Law, etc.) offered separate programs loosely connected to the other. The creation of IUPUI in 1969 more closely fused the various separate entities of Indiana University in Indianapolis together. Records include correspondence, minutes, reports, publications, and other materials.

Delta Psi Kappa was a "professional fraternity for women in the fields of health, physical education, and recreation". Founded in 1916 at the Normal College of the American Gymnastic Union, Delta Psi Kappa would eventually spread to a large number of other colleges and universities with programs in the aforementioned fields. Active into the 1990s, the organization remained focused on health and physical education and participated in numerous activities with other organizations who shared their goals.

The Indianapolis Foundation was created in 1916 by the resolution of three financial institutions, the Fletcher Trust Company, Indiana Trust Company, and Union Trust Company. It was officially introduced as one of the first community foundations in the United States in the January 5, 1916, edition of the Indianapolis Star. According to the resolution, income from the Indianapolis Foundation would "be dispersed by said companies on the written order of a board of trustees for such charitable uses as well in its judgment promote the welfare of persons now or hereafter residing in Indianapolis, Indiana." The foundation began making grants in 1924 and today continues to give to Indianapolis organizations to help improve the quality of life in the city.

The National FFA Organization, originally called the Future Farmers of America, was founded in 1928 as a national organization for boys in rural, farming communities. Its original purpose, the education of youth in agricultural fields of study, is still recognized through its current programs. Today, the mission of the National FFA Organization is to make a positive difference in the lives of students by developing their potential for premier leadership, personal growth, and career success through agricultural education. Through educational programs the FFA teaches students how to become active in their communities and successful in their occupation. FFA membership includes junior high, high school, and college students and totals approximately 450,000. This collection contains correspondence, minutes, newsletters, publications, reports, audio cassettes, video cassettes, and photographs.

Kiwanis International, briefly called the Supreme Lodge Benevolent Order Brothers, was officially chartered in 1915 as a club for businessmen that also had social and commercial benefits. That original intent evolved quickly into a club for businessmen who wanted to improve their communities, hence the 1920 motto "we build." Today, Kiwanis International is a global organization, with numerous projects dedicated primarily to their current motto of "serving the children of the world." The Downtown Kiwanis Club of Indianapolis was the first Kiwanis club in Indiana, founded in 1916, and currently has more than 250 members, making it the largest Kiwanis Club in Indiana. This collection contains by-laws, minutes, correspondence, newsletters, club rosters, tax information, yearbooks, scrapbooks, and brochures.

Junior Achievement, Inc. (JA) was founded in 1919 as the Boys' and Girls' Bureau of the Eastern States League. Embracing the concept of "learning by doing," the leaders of the Bureau dedicated themselves to teaching urban youth proper business practice and methods. They accomplished this through hands-on training in management and production. For much of its history, JA used one program to teach business to high school students. Beginning in the 1970s, JA started to expand its programs to include Kindergarten, Middle School, and college students. Over the last 20 years, the programs of JA have changed immensely. While the face of JA has changed, the mission of teaching youth about business remains at the core of Junior Achievement. Today, JA continues to be one of the most influential business education organizations worldwide

Altrusa International, Inc. is an international service organization for professional and executive business women with membership on a limited classification basis. The National Association of Altrusa Clubs, founded in 1917 as Altrusa Institute, was the first national organization of business and professional women. In 1935 Altrusa became international and the name was changed to International Association of Altrusa Clubs, Inc. The organization's name was changed again in June 1947, to Altrusa International, Inc. The Indianapolis Altrusa Club was formed in April 1917. Its programs and activities have included vocational education and guidance, senior citizens programs, civic service and community service projects, financial assistance for graduate women from other countries and literacy related programs. The organization's objectives are to cultivate friendly relationships and solidarity among business and professional women to encourage mutual helpfulness; to provide vocational information and service to women of all ages; to encourage members to actively participate in community, national and international affairs, and to promote educational and cultural training. The records consist of legal documents, board and committee records, meeting files, financial records, correspondence, publications, special event materials, scrapbooks, news clippings and photographs.

In 1947 Charles Edward Marsh founded the Public Welfare Foundation to render direct financial assistance to the needy. His purpose, to offer the greatest good to the greatest number of people, symbolized the efforts of the foundation he created. His method of distributing money, called the agent system, dispersed financial assistance to provide for the immediate needs of individuals. As tax laws required more detailed reporting, the foundation began to phase out the agent system and created a more formal method of receiving proposals from organizations worldwide. With a commitment to supporting organizations that help people overcome barriers to full participation in society, the foundation had distributed more than $400 million in grants by 2007. Its purpose continues in the spirit of Charles Marsh to focus on "ensuring the fundamental rights and opportunities for people in need."

American City Bureau, a fundraising consulting firm, works with not for profit organizations to design and run fund raising campaigns. Established in 1913 by Edgar and Harold Buttenheim, the company merged with Beaver and Associates in 1963. The firm has worked on capital campaigns on the national and local level. American City Bureau has been instrumental in developing campaigns for organizations such as the Young Men's Christian Association,(YMCA), the Young Women's Christian Association, (YWCA), United Fund, and the Salvation Army. The records detail the fund raising efforts and campaigns of the American City Bureau and its predecessor origins. It consists of 4 page reports of campaigns from Howard T. Beaver Associates, (later Beaver and Associates) from 1936-1963, campaign information from American City Bureau from 1944 -1995, conference addresses and programs, from 1938-1978, promotional materials and publications from 1919- 1973, and their newsletter, Bureau News from 1920-1976.

The Social Health Association of Central Indiana began as the Anti-Syphilis League of Indiana in 1938. Its purpose was to eradicate venereal diseases, particularly syphilis and gonorrhea, and the conditions which contributed to its proliferation. In 1939, the name was changed to the Indiana Social Hygiene Association. In 1943, their mission included the eradication of venereal diseases; the battle against prostitution and sexual delinquency; the promotion of sex education and appropriate sexual behavior; and the support of family and marriage relations. As the organization's focus evolved, it underwent a name change to the Social Health Association of Indianapolis and Marion County, and in the 1960s, became more involved in sex education, developing materials for elementary and secondary schools and education professionals. In 1976, the name changed to the Social Health Association of Central Indiana as it began to develop programs for areas outside of Marion County. In the 1980s, the organization added AIDS education to its curriculum and in the 1990s it added "Life Skills" education. The agency changed its name to Social Health Association of Indiana in 2000; in the 2000s its focus shifted to puberty education, internet safety, and bullying prevention. In 2018, it became LifeSmart Youth, Inc. and focused on health and behavior education. The collection consists of board of directors and committee minutes, administrative records, publications, program materials, sex education plans, teaching materials, and audio materials including class instruction, advertisements and radio broadcasts.

Department of Nutrition and Dietetics at Indiana University Purdue University- Indianapolis (IUPUI) was founded in 1918. The department offered a graduate-level dietetic internship program where interns worked at Indiana University Medical Center and Riley Hospital for Children.

Sigma Theta Tau International (STTI) is an honor society for nurses committed to fostering excellence, scholarship and leadership in nursing to improve health care worldwide. STTI is a society of nursing leaders who are active in research, education, and practice in the field. As an honor society, it recognizes those who excel in their field and emphasizes the importance of continued professional enhancement. The International Center for Nursing Scholarship, located on the campus of Indiana University Purdue University Indianapolis (IUPUI) in Indianapolis, Indiana, is the headquarters of STTI.

Mary Fink was an active volunteer and leader in the Jewish community. An active member of the National Council of Jewish Women, she served as the organization's president from 1962-1964. As a volunteer in the Indianapolis community, she worked on a variety of governing boards and committees aimed at community betterment. This collection contains information about her and her activities in the Indianapolis community.

Sigma Theta Tau International (STTI) is an honor society for nurses committed to fostering excellence, scholarship, and leadership in nursing to improve health care worldwide. STTI is a society of nursing leaders who are active in research, education, and practice in the field. As an honor society, it recognizes those who excel in their field and emphasizes the importance of continued professional enhancement. Alpha Chapter, at Indiana University Purdue University Indianapolis (IUPUI) in Indianapolis, Indiana, is the founding chapter of STTI.

Physical therapy has long had a presence in the treatment offered in the Indiana University hospitals. In 1956 a bachelor of science program in physical therapy was established under the division of Allied Health in the School of Medicine. Graduate programs in physical therapy were later established. The Department of Physical Therapy is currently under the IU School of Health and Rehabilitation Sciences. Records include correspondence, reports, patient files, publications, and other materials.

This collection contains the information compiled by Sara Sanderson for an article based on a diary written by Marguerite Richey in 1928 while in New York City with her husband, Oakley Richey. Oakley Richey was a Herron School of Art graduate and instructor. The diary was discovered by Sara Sanderson who subsequently researched and wrote an article based on the diary.